| Identification | Back Directory | [Name]
Ethanone, 1-[1-ethyl-5-[4-[(4-hydroxy-1-piperidinyl)methyl]-2-thiazolyl]-1H-indol-3-yl]-2,2,2-trifluoro-, 2-(2-benzothiazolyl)hydrazone, (1Z)- | [CAS]
2484811-36-9 | [Synonyms]
ATX inhibitor 16
Ethanone, 1-[1-ethyl-5-[4-[(4-hydroxy-1-piperidinyl)methyl]-2-thiazolyl]-1H-indol-3-yl]-2,2,2-trifluoro-, 2-(2-benzothiazolyl)hydrazone, (1Z)- | [Molecular Formula]
C28H27F3N6OS2 | [MOL File]
2484811-36-9.mol | [Molecular Weight]
584.68 |
| Hazard Information | Back Directory | [Uses]
ATX inhibitor 16 is a potent ATX inhibitor with an IC50 of 0.0021 μM. ATX inhibitor 16 shows excellent anti-proliferative activities in breast cancer cells[1]. | [References]
[1] Lei H,et al. Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects. Eur J Med Chem. 2020 Sep 1;201:112456. DOI:10.1016/j.ejmech.2020.112456 |
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