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2485-33-8

2485-33-8 Structure

2485-33-8 Structure
IdentificationBack Directory
[Name]

H-(2S,4R)-GAMMA-HYDROXY-GLU-OH
[CAS]

2485-33-8
[Synonyms]

H-(2S,4R)-Glu(g-OH)-OH
H-(2S,4R)-γ-Hydroxy-Glu-OH
H-(2S,4R)-GLU(GAMMA-OH)-OH
H-(2S,4R)-g-Hydroxy-Glu-OH
H-(2S,4R)-GAMMA-HYDROXY-GLU-OH
(4R)-4-Hydroxy-L-glutaMic Acid
erythro-4-Hydroxy-L-glutaMic Acid
(2S,4R)-γ-Hydroxy-L-glutamic acid
(2S,4R)-4-Hydroxy-L-glutaMic Acid
L-Glutamic acid, 4-hydroxy-, (4R)-
(2S,4R)-g-4-Hydroxy-L-glutaMic Acid
(2S,4R)-GAMMA-HYDROXY-GLUTAMIC ACID
erythro-(4R)-4-Hydroxy-L-glutamic acid
(2S,4R)-2-Amino-4-hydroxypentanedioic acid
4-aMino-3,4-dideoxy-D-erythro-pentaric acid
(S)-2-AMINO-[(R)-4],5-DIHYDROXY-OXOPENTANOIC ACID
[Molecular Formula]

C5H9NO5
[MDL Number]

MFCD00672375
[MOL File]

2485-33-8.mol
[Molecular Weight]

163.13
Chemical PropertiesBack Directory
[Melting point ]

>159°C (dec.)
[Boiling point ]

458.7±45.0 °C(Predicted)
[density ]

1.595±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[solubility ]

DMSO (Slightly), Water (Slightly)
[form ]

Solid
[pka]

2.15±0.10(Predicted)
[color ]

White to Off-White
[optical activity]

[α]/D 20.5±1.5°, c = 1 in H2O
[BRN ]

1725871
[Stability:]

Hygroscopic
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

(2S,4R)-4-Hydroxy-L-glutamic Acid is a metabolite of Glutamic acid (G596960).
[Definition]

ChEBI: Erythro-4-hydroxy-L-glutamic acid is a 4-hydroxy-L-glutamic acid. It has a role as a Saccharomyces cerevisiae metabolite. It is functionally related to a L-glutamic acid. It is a conjugate acid of an erythro-4-hydroxy-L-glutamate(1-).
[Biological Activity]

(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptorsmGlu1amGlu2and mGlu8a in a dose-dependent manner. ''Substrate for aminotransferase; pharmacological characterization at human glutamate transporter subtypes 1-3; for studying structure-activity relationships (SAR) for ionotropic and metabotropic glutamate receptors.
[IC 50]

Human Endogenous Metabolite
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