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2490419-48-0

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2490419-48-0 Structure

2490419-48-0 Structure
IdentificationBack Directory
[Name]

Azido-PEG10-COOtBu
[CAS]

2490419-48-0
[Synonyms]

Azido-PEG10-Boc
N3-PEG10-COOtBu
Azido-PEG10-COOtBu
Azido-PEG10-CH2COOtBu
[Molecular Formula]

C27H53N3O12
[MOL File]

2490419-48-0.mol
[Molecular Weight]

611.73
Chemical PropertiesBack Directory
[storage temp. ]

Storage temp. 2-8°C
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Azido-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[IC 50]

PEGs; Alkyl/ether
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

Azido-PEG10-COOtBu(2490419-48-0)1HNMR
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