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24928-15-2

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24928-15-2 Structure

24928-15-2 Structure
IdentificationBack Directory
[Name]

PHORBOL 12,13-DIACETATE
[CAS]

24928-15-2
[Synonyms]

PDA
PHORBOL-DIACETATE
phorbol10,11-diacetate
phorbol11,12-diacetate
PHORBOL 12,13-DIACETATE
Phorbol 12,13-Diacetate >99%
PHORBOL 12,13-DIACETATE, 4BETA
l)-1,1,6,8-alpha-tetramethyl-,9,9a-diacetate,(+)
5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-alpha,16-beta,4,4a,7a-alpha,7b,
8,9,9a-decahydro-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-(hydroxymethy
(1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-5-oxo-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulene-4aβ,7bα,9β,9aα-tetrol 9,9a-diacetate
(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-(hydroxyMethyl)-1,1,6,8-tetraMethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl diacetate
5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9,9a-bis(acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-
[Molecular Formula]

C24H32O8
[MDL Number]

MFCD00036735
[MOL File]

24928-15-2.mol
[Molecular Weight]

448.51
Chemical PropertiesBack Directory
[Boiling point ]

477.23°C (rough estimate)
[density ]

1.1793 (rough estimate)
[refractive index ]

1.4480 (estimate)
[storage temp. ]

−20°C
[solubility ]

H2O: soluble
[form ]

powder
[color ]

white
[Water Solubility ]

H2O: soluble
[BRN ]

2317312
[InChIKey]

OMHXSAMFEJVCPT-XQOWHXTBSA-N
[SMILES]

C[C@@H]1[C@@H](OC(C)=O)[C@]2(OC(C)=O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C
Safety DataBack Directory
[Hazard Codes ]

T+
[Risk Statements ]

26/27/28-36/37/38
[Safety Statements ]

26-27-36/37/39-45
[RIDADR ]

UN 2811 6.1/PG 3
[WGK Germany ]

3
[RTECS ]

GZ0651000
[F ]

8-10
[HazardClass ]

6.1(a)
[PackingGroup ]

II
[HS Code ]

2915290000
[Storage Class]

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
[Hazard Classifications]

Acute Tox. 1 Inhalation
Acute Tox. 2 Dermal
Acute Tox. 2 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

Phorbol 12,13-diacetate may be used to stimulate protein kinase C (PKC) for phosphorylation of retinal proteins.
[General Description]

Phorbol ester with enhanced hydrophilicity.
[Biochem/physiol Actions]

Phorbol 12,13-diacetate (PDA) serves as a protein kinase C (PKC). It induces arrest in translocation in rod photoreceptors. PDA facilitates PKC in regulating airway contractility by inducing transient relaxation after a sustained contraction of the human isolated bronchus. PDA improves the synaptic transmission of nociceptive parabrachioamygdaloid (PBA) input onto neurons of the capsular central amygdaloid (CeAC) nucleus via activating PKC and extracellular-regulated kinase (ERK).
24928-15-2 suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Telephone: 18930552037
Website: www.chemicalbook.com/showsupplierproductslist13285/0_en.htm
Company Name: Syntechem Co.,Ltd  
Telephone:
Website: www.syntechem.com
Company Name: Sigma-Aldrich  
Telephone: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: DAYANG CHEM (HANGZHOU) CO.,LTD  
Telephone: +86-88938639 +86-17705817739
Website: www.dycnchem.com
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