| Identification | Back Directory | [Name]
RO3201195 | [CAS]
249937-52-8 | [Synonyms]
RO3201195
Ro-3201195, 10 mM in DMSO
Methanone, [5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl][3-(2,3-dihydroxypropoxy)phenyl]- | [Molecular Formula]
C19H18FN3O4 | [MOL File]
249937-52-8.mol | [Molecular Weight]
371.36 |
| Chemical Properties | Back Directory | [Boiling point ]
644.7±55.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.43±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
RO3201195 (compound 1) is an inhibitor of p38 MAPK. RO3201195 inhibits WS cell proliferation with IC50 value of 190 nM[1]. | [References]
[1] Mark C. Bagley, et al. The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells. Org Biomol Chem. 2016, 14, 3. DOI:10.1039/c5ob02229k |
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