| Identification | Back Directory | [Name]
Ethanol, 2-[[[7-(2-fluorophenyl)-4,7-dihydro-2,2-dioxido-3H-1,2-oxathiino[6,5-c]pyrazol-5-yl]methyl][(4-fluorophenyl)methyl]amino]- | [CAS]
2499488-78-5 | [Synonyms]
BuChE-IN-3
Ethanol, 2-[[[7-(2-fluorophenyl)-4,7-dihydro-2,2-dioxido-3H-1,2-oxathiino[6,5-c]pyrazol-5-yl]methyl][(4-fluorophenyl)methyl]amino]- | [Molecular Formula]
C21H21F2N3O4S | [MOL File]
2499488-78-5.mol | [Molecular Weight]
449.47 |
| Hazard Information | Back Directory | [Uses]
BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC50 of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity[1]. | [References]
[1] Zhang Z, et al. The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors. Eur J Med Chem. 2020 Sep 1;201:112273. DOI:10.1016/j.ejmech.2020.112273 |
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