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2500-80-3

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2500-80-3 Structure

2500-80-3 Structure
IdentificationBack Directory
[Name]

4'-thioadenosine
[CAS]

2500-80-3
[Synonyms]

Nsc 82219
4'-thioadenosine
Adenosine, 4'-thio-
(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrothiophene-3,4-diol
[Molecular Formula]

C10H13N5O3S
[MDL Number]

MFCD28342914
[MOL File]

2500-80-3.mol
[Molecular Weight]

283.31
Chemical PropertiesBack Directory
[Melting point ]

125.4-126.3 °C
[Boiling point ]

657.8±65.0 °C(Predicted)
[density ]

2.08±0.1 g/cm3(Predicted)
[pka]

13.05±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

4’-Thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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