Log in | Join Free | china | japan | germany
ChemicalBook--->CAS DataBase List--->2502156-03-6

2502156-03-6

Request For Quotation
2502156-03-6 Structure

2502156-03-6 Structure
IdentificationBack Directory
[Name]

PROTAC KRASG12C Degrader-LC-2
[CAS]

2502156-03-6
[Synonyms]

LC-2
PROTAC KRASG12C Degrader-LC-2
[MDL Number]

MFCD32857122
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 50 mg/mL (44.14 mM; ultrasonic and warming and heat to 80°C)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

LC-2 is a von Hippel-Lindau-based PROTAC which can degrade endogenous KRAS G12C. It covalently binds KRAS G12C with a MARTX849 warhead and recruits the E3 ligase VHL which degrades the KRAS G12C and suppresses MAPK signaling in homozygous and heterzygous KRAS G12C cell lines.
[storage]

Store at -20°C
2502156-03-6 suppliers list
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203 , +undefined18143011203
Website: www.chemextension.com/
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel: +8613720134139 , +8613720134139
Website: http://www.jknbiochem.com/
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 15221909166
Website: www.bidepharm.com
Company Name: DebyeTec.com Inc.  
Tel: 18086626237 18086626237
Website: https://www.debyetec.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 17754423994 17754423994
Website: https://www.biochempartner.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ:65489617 15618227136
Website: www.superlan-chem.com
Company Name: Jilin Province Woda Biotechnology Co., Ltd.  
Tel: 13504435624
Website: https://www.wodapro.com
Company Name: DC Chemicals  
Tel: 021-58447131 13564518121
Website: https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm
Company Name: Wuhan Topule  
Tel: +86-02787215551 +86-19945035818
Website: http://www.topule.com/
Company Name: Shanghai Haohong Pharmaceutical Co., Ltd.  
Tel: 400-8210725 4008210725
Website: https://www.leyan.com/
Company Name: Hubei Kele Fine Chemical Co., Ltd  
Tel: 027-59101668 19945030958
Website: http://www.kerle.cn
Company Name: Changzhou Bojia Biomedical Technology Co., Ltd.  
Tel: 2122619822
Website: www.chemicalbook.com/showsupplierproductslist849747/0.htm
Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
Tel: 0431-80514535 19917294565
Website: www.chemextension.com
Company Name: Hubei Benofu Chemical Technology Co., Ltd.  
Tel: 15307183689
Website: www.chemicalbook.com/ShowSupplierProductsList497616/0.htm
Company Name: Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.  
Tel: +86-027-59232304 15387063101
Website: https://www.yingnor.com/
Company Name: Beijing InnoChem Science & Technology Co., Ltd.  
Tel: 15652467323 15652467323
Website: www.inno-chem.com.cn
Tags:2502156-03-6 Related Product Information
2249750-24-9 1801547-16-9 2249944-99-6 2369022-68-2 2249944-98-5 2381320-35-8 2098487-75-1 2249750-23-8 2163793-38-0