| Identification | Back Directory | [Name]
3H-1,2,4-Triazol-3-one, 4-[4-[[4-[[1-[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]-4-piperidinyl]methyl]-1-piperazinyl]methyl]phenyl]-5-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-2,4-dihydro-, hydrochloride (1:1) | [CAS]
2503036-46-0 | [Synonyms]
RNK-05047
3H-1,2,4-Triazol-3-one,4-[4-[[4-[[1-[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-Chemicalbookyl]acetyl]-4-piperidinyl]methyl]-1-piperazinyl]methyl]
3H-1,2,4-Triazol-3-one, 4-[4-[[4-[[1-[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]-4-piperidinyl]methyl]-1-piperazinyl]methyl]phenyl]-5-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-2,4-dihydro-, hydrochloride (1:1) | [Molecular Formula]
C47H53ClN10O4S.ClH |
| Hazard Information | Back Directory | [Uses]
PROTAC BRD4 Degrader-21 (Comp 74) is a PROTAC degrader of BRD4. PROTAC BRD4 Degrader-21 displays significant tumor growth inhibition in tumor -bearing xenograft models in mice and can be used for anticancer research[1]. | [References]
[1] Weiwen Ying, et.al. Methods and compositions for targeted protein degradation |
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