| Identification | Back Directory | [Name]
crebanine | [CAS]
25127-29-1 | [Synonyms]
Crebanin
crebanine
5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-9,10-dimethoxy-7-methyl-, (7R)-
(R)-9,10-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C20H21NO4 | [MDL Number]
MFCD01658977 | [MOL File]
25127-29-1.mol | [Molecular Weight]
339.389 |
| Chemical Properties | Back Directory | [Melting point ]
126 °C | [Boiling point ]
488.2±45.0 °C(Predicted) | [density ]
1.266±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Cryst. | [pka]
6?+-.0.20(Predicted) | [color ]
Off-white to light yellow |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P305+P351+P338 | [Toxicity]
mouse,LD50,intraperitoneal,24230ug/kg (24.23mg/kg),BEHAVIORAL: IRRITABILITYBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDLUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION,Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 20, Pg. 422, 1989. |
| Hazard Information | Back Directory | [Chemical Properties]
Milky white crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from dibutyl phthalate. | [Uses]
Crebanine is an aporphine alkaloid which helps sensitize TNF-α induced apoptosis and suppress human lung adenocarcinoma. Known to exhibit anticancer properties. | [storage]
4°C, protect from light |
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