| Identification | Back Directory | [Name]
Benzamide, N-[5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]-4-[(trifluoromethyl)thio]- | [CAS]
2519410-44-5 | [Synonyms]
N-(5-(3,5-Dichlorophenyl)-1,3,4-oxadiazol-2-yl)-4-((trifluoromethyl)thio)benzamide
Benzamide, N-[5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]-4-[(trifluoromethyl)thio]- | [Molecular Formula]
C16H8Cl2F3N3O2S | [MOL File]
2519410-44-5.mol | [Molecular Weight]
434.22 |
| Chemical Properties | Back Directory | [density ]
1.63±0.1 g/cm3(Predicted) | [solubility ]
DMF: 30 mg/ml
DMSO: 30 mg/ml
DMSO: PBS (pH 7.2) (1:3): 0.25 mg/ml
Ethanol: 1 mg/ml | [pka]
9.69±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
HSGN-218 is an antibacterial agent with low Caco-2 permeability. HSGN-218 efficiently inhibits the growth of different C. difficile species with MIC values ranging from 0.007 μM to 0.07 μM.[1] | [References]
[1] Naclerio GA, et al. Ultrapotent Inhibitor of Clostridioides difficile Growth, Which Suppresses Recurrence In Vivo. J Med Chem. 2020 Oct 22;63(20):11934-11944. DOI:10.1021/acs.jmedchem.0c01198 |
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