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253168-94-4

253168-94-4 Structure

253168-94-4 Structure
IdentificationBack Directory
[Name]

3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
[CAS]

253168-94-4
[Synonyms]

Apremilast int
Apremilast Impurity 42
ApreMilast interMediate
Apremilast EP Impurity H
Apremilast Intermediate I
1-(3-Ethoxy-4-Methoxyphenyl)-2-MethylsulfonylethylaMine
1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine
1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine
2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine
1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine
1.1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine
1-(3-Ethoxy-4-methoxyphenyl)-2- (methylsulofonyl)ethan-1-amine
3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine
3-ethoxy-4-methoxy-a-[(methylsulfonyl)methyl]-Benzenemethanamine
BenzeneMethanaMine, 3-ethoxy-4-Methoxy-a-[(Methylsulfonyl)Methyl]-
3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethaMine
Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-
3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine Apremilast
1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine (~10% inorganics)
3-Ethoxy-4-methoxy-alpha-[(methylsulfonyl)methyl]-benzenemethanamine 1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethylamine
[EINECS(EC#)]

807-312-3
[Molecular Formula]

C12H19NO4S
[MDL Number]

MFCD27665207
[MOL File]

253168-94-4.mol
[Molecular Weight]

273.349
Chemical PropertiesBack Directory
[Melting point ]

120 °C
[Boiling point ]

469.6±45.0 °C(Predicted)
[density ]

1.195±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
[form ]

Solid
[pka]

6.84±0.10(Predicted)
[color ]

White to Off-White
[InChI]

InChI=1S/C12H19NO4S/c1-4-17-12-7-9(5-6-11(12)16-2)10(13)8-18(3,14)15/h5-7,10H,4,8,13H2,1-3H3
[InChIKey]

BXUJVINGXQGNFD-UHFFFAOYSA-N
[SMILES]

C1(C(CS(C)(=O)=O)N)=CC=C(OC)C(OCC)=C1
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
[HS Code ]

2922.50.4000
Hazard InformationBack Directory
[Uses]

1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H
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