| Identification | Back Directory | [Name]
proxibarbal | [CAS]
2537-29-3 | [Synonyms]
Axeen
HH-184
Centralgol
Centralgyl
Hydroxydial
proxibarbal
5-allyl-5-(2-hydroxypropyl)barbituric acid
5-(2-hydroxypropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-hydroxypropyl)-5-(2-propen-1-yl)- | [EINECS(EC#)]
219-803-4 | [Molecular Formula]
C10H14N2O4 | [MDL Number]
MFCD00867997 | [MOL File]
2537-29-3.mol | [Molecular Weight]
226.231 |
| Safety Data | Back Directory | [RIDADR ]
3249 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
LD50 intraperitoneal in mouse: 2500mg/kg |
| Hazard Information | Back Directory | [Uses]
Relaxant (smooth muscle);analgesic; anti-inflammatory. | [Definition]
ChEBI: Proxibarbal is a member of barbiturates. | [Brand name]
Toness (Angelini Francesco,Italy). | [in vivo]
Proxibarbaland Valofan are tautomeric drugs which interconvert rapidly in solution. In the present study, the urinary excretion of these two drugs is investigated in two subjects after separate oral administration. In both cases, only Proxibarbalis found in urine, while the excretion of Valofan is negligible or non-detectable. More than half of a dose remains unaccounted for after Proxibarbal administration, and more than three quarters after Valofan administration[1]. |
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