| Identification | Back Directory | [Name]
Neomycin B Hydrochloride | [CAS]
25389-99-5 | [Synonyms]
Neomycin B hydrochloride
D-Streptamine,O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(1(R)3)-O-b-D-ribofuranosyl-(1(R)5)-O-[2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl-(1(R)4)]-2-deoxy-, hydrochloride (1:1) | [Molecular Formula]
C23H46N6O13.ClH |
| Chemical Properties | Back Directory | [alpha ]
D20 +57° (H2O) | [Contact allergens]
Neomycin is an antibiotic complex of the aminoglycosides
group, extracted from Streptomyces fradiae. It is composed
of neomycin A (neamin) and an isomer neobiosamin, either neomycin B (framycetin or Soframycin®) or neomycin C.
Its use has been progressively forbidden in cosmetics and
as an additive for animal feed. Occupational contact dermatitis
occurs in workers at animal feed mills, in veterinaries,
or in health workers. Nonoccupational dermatitis mainly
concerns patients with chronic dermatitis, leg ulcers, or
chronic otitis. Cross-sensitivity is usual with other aminoglycosides
(amikacin, arbekacin, butirosin, dibekacin, gentamicin,
isepamicin, kanamycin, paromomycin,
ribostamycin, sisomycin, tobramycin), is rare with netilmicin
and streptomycin, but nonexistent with spectinomycin. |
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