ChemicalBook--->CAS DataBase List--->25422-31-5

25422-31-5

25422-31-5 Structure

25422-31-5 Structure
IdentificationBack Directory
[Name]

FIBRINOPEPTIDE A, HUMAN
[CAS]

25422-31-5
[Synonyms]

FPA, HUMAN
FIBRINOPEPTIDE A
ADSGEGDFLAEGGGVR
Human fibrinopeptide A
fibrinogen alphaA(1-16)
ADSGEGDFLAEGGGVR, HUMAN
FIBRINOPEPTIDE A, HUMAN
FIBRINOPEPTIDE A, HUMAN USP/EP/BP
ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-VAL-ARG
ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-GLY-VAL-ARG
Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg-OH
H-ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-GLY-VAL-ARG-OH
ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-GLY-VAL-ARG HUMAN
L-Ala-L-Asp-L-Ser-Gly-L-Glu-Gly-L-Asp-L-Phe-L-Leu-L-Ala-L-Glu-Gly-Gly-Gly-L-Val-L-Arg-OH
[Molecular Formula]

C63H97N19O26
[MDL Number]

MFCD00076437
[MOL File]

25422-31-5.mol
[Molecular Weight]

1536.56
Chemical PropertiesBack Directory
[density ]

1.53±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

Solid
[pka]

3.32±0.10(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Fibrinopeptide A human has been used for protein control experiments performed during sandwich ELISA microarray assay to distinguish between plasma and serum fibrinogen samples. It has also been used in a peptide mixture along with BSA (bovine serum albumin) to ascertain the relation between fragmentation voltage and peptide ion drift time for IMS-MS (ion mobility spectrometry coupled with mass spectrometry).
[General Description]

Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen protein, on cleavage by thrombin. It is composed of 16 amino acids.
[Biochem/physiol Actions]

Fibrinogen plays essential roles in coagulation of blood, wound healing, platelet aggregation and has roles in various other physiological processes. Increase in the levels of fibrinopeptide A (FPA) is found in multiple disorders such as coronary artery disease, disseminated intravascular coagulation, arterial thrombosis, deep venous thrombosis and cancers.
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