| Identification | Back Directory | [Name]
Betulinic aldehyde oxime, 97%, Semi-Synthetic | [CAS]
25613-12-1 | [Synonyms]
Betulinic Aldehyde oxime
Betulinic aldehyde oxime, 97%, Semi-Synthetic | [Molecular Formula]
C30H49NO2 | [MDL Number]
MFCD32692727 | [MOL File]
25613-12-1.mol | [Molecular Weight]
455.716 |
| Hazard Information | Back Directory | [Uses]
Betulinic aldehyde oxime (Compound 31) is a betulin (HY-N0083) derivative that has antimicrobial properties against E. aerogenes, E. coli, E. faecalis, P. aeruginosa, S. aureus, and C. albicans. Betulinic aldehyde oxime displays cytotoxicity towards hepatocytes, with an IC50 of 25 μM[1]. | [Biological Activity]
Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1 It is active against E. aerogenes, E. coli, E. faecalis, P. aeruginosa, S. aureus, and C. albicans, as well as L. donovani amastigotes, when used at a concentration of 50 μM.1,2 Betulinic aldehyde oxime (50 μM) is cytotoxic to Huh7 hepatocellular carcinoma cells.2 | [storage]
-20°C | [References]
1.Alakurtti, S., Bergstr?m, P., Sacerdoti-Sierra, N., et al.Anti-leishmanial activity of betulin derivativesJ. Antibiot. (Tokyo)63(3)123-126(2010)
2.Haque, S., Nawrot, D.A., Alakurtti, S., et al.Screening and characterisation of antimicrobial properties of semisynthetic betulin derivativesPLoS One9(7)e102696(2014)
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ChemeGen
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18818260767 |
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https://www.chemegen.com |
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