| Identification | Back Directory | [Name]
3'-O-(2-Methoxyethyl)guanosine | [CAS]
256224-03-0 | [Synonyms]
3’-O-MOE-G
3'-O-(2-Methoxyethyl)guanosine
Guanosine, 3'-O-(2-methoxyethyl)- (9CI) | [Molecular Formula]
C13H19N5O6 | [MDL Number]
MFCD31537260 | [MOL File]
256224-03-0.mol | [Molecular Weight]
341.32 |
| Chemical Properties | Back Directory | [form ]
Solid | [color ]
White to off-white | [InChI]
InChI=1S/C13H19N5O6/c1-22-2-3-23-9-6(4-19)24-12(8(9)20)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-6,8-9,12,19-20H,2-4H2,1H3,(H3,14,16,17,21)/t6-,8-,9-,12-/m1/s1 | [InChIKey]
BPFOZTYDUWLNNN-WOUKDFQISA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](O)[C@@H]1OCCOC |
| Hazard Information | Back Directory | [Description]
3'-O-(2-Methoxyethyl)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7). | [Uses]
3'-O-(2-Methoxyethyl)guanosine is a remarkable modified nucleoside with immense potential in the field of antiviral drug discovery. This exquisite compound takes center stage in targeting viral RNA-dependent RNA polymerases, thus rendering it a powerful weapon in research of respiratory syncytial virus (RSV) and hepatitis C virus (HCV).
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