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256224-03-0

256224-03-0 Structure

256224-03-0 Structure
IdentificationBack Directory
[Name]

3'-O-(2-Methoxyethyl)guanosine
[CAS]

256224-03-0
[Synonyms]

3’-O-MOE-G
3'-O-(2-Methoxyethyl)guanosine
Guanosine, 3'-O-(2-methoxyethyl)- (9CI)
[Molecular Formula]

C13H19N5O6
[MDL Number]

MFCD31537260
[MOL File]

256224-03-0.mol
[Molecular Weight]

341.32
Chemical PropertiesBack Directory
[InChI]

InChI=1S/C13H19N5O6/c1-22-2-3-23-9-6(4-19)24-12(8(9)20)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-6,8-9,12,19-20H,2-4H2,1H3,(H3,14,16,17,21)/t6-,8-,9-,12-/m1/s1
[InChIKey]

BPFOZTYDUWLNNN-WOUKDFQISA-N
[SMILES]

OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](O)[C@@H]1OCCOC
Hazard InformationBack Directory
[Description]

3'-O-(2-Methoxyethyl)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
[Uses]

3'-O-(2-Methoxyethyl)guanosine is a remarkable modified nucleoside with immense potential in the field of antiviral drug discovery. This exquisite compound takes center stage in targeting viral RNA-dependent RNA polymerases, thus rendering it a powerful weapon in research of respiratory syncytial virus (RSV) and hepatitis C virus (HCV).
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