| Identification | Back Directory | [Name]
Pyrazolo[4'',3'':3',4']cyclohepta[1',2':4,5]thieno[3,2-d]pyrimidin-10(9H)-one, 8-(2S)-1-azabicyclo[2.2.2]oct-2-yl-2,4,5,6-tetrahydro- | [CAS]
2562329-13-7 | [Synonyms]
(S)-Cdc7-IN-18
Pyrazolo[4'',3'':3',4']cyclohepta[1',2':4,5]thieno[3,2-d]pyrimidin-10(9H)-one, 8-(2S)-1-azabicyclo[2.2.2]oct-2-yl-2,4,5,6-tetrahydro- | [Molecular Formula]
C19H21N5OS | [MOL File]
2562329-13-7.mol | [Molecular Weight]
367.47 |
| Hazard Information | Back Directory | [Uses]
(S)-Cdc7-IN-18 is a potent inhibitor of CDC7. Overexpression of huCdc7 promotes overactivation of MCM2, an important marker of tumor cells, and thus promotes aberrant proliferation of tumor cells. (S)-Cdc7-IN-18 has the potential for the research of cancer diseases (extracted from patent WO2020239107A1, compound 1-1)[1]. | [References]
[1] Gang Li, et al. Tetracyclines as Cdc7 inhibitors. Patent WO2020239107A1.
[2] Li Gang, et al. Tetracyclic compounds as cdc7 inhibitors. WO2020239107A1. |
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