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256337-10-7

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256337-10-7 Structure

256337-10-7 Structure
IdentificationBack Directory
[Name]

Geldanamycin, 17-demethoxy-17-[[3-[[4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxobutyl]amino]propyl]amino]-
[CAS]

256337-10-7
[Synonyms]

Geldanamycin, 17-demethoxy-17-[[3-[[4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxobutyl]amino]propyl]amino]-
[Molecular Formula]

C39H53N5O11
[MDL Number]

MFCD09802285
[MOL File]

256337-10-7.mol
[Molecular Weight]

767.88
Chemical PropertiesBack Directory
[Boiling point ]

1009.7±65.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[pka]

8.62±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

17-GMB-APA-GA is an ADC Cytotoxin. 17-GMB-APA-GA is a potent HSP90 inhibitor and used for latent T. gondii infection research[1].
[IC 50]

HSP90; Traditional Cytotoxic Agents
[References]

[1] Sergio O Angel, et al. A Review of Recent Patents on the Protozoan Parasite HSP90 as a Drug Target. Recent Pat Biotechnol. 2013 Apr;7(1):2-8. DOI:10.2174/1872208311307010002
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