| Identification | Back Directory | [Name]
Spiro[2H-indene-2,4'-piperidin]-1-amine, 1'-[2-(2,3-dichlorophenyl)thiazolo[4,5-b]pyrazin-6-yl]-1,3-dihydro-, (1S)- | [CAS]
2565765-13-9 | [Synonyms]
JC-010a
Spiro[2H-indene-2,4'-piperidin]-1-amine, 1'-[2-(2,3-dichlorophenyl)thiazolo[4,5-b]pyrazin-6-yl]-1,3-dihydro-, (1S)- | [Molecular Formula]
C24H21Cl2N5S | [MOL File]
2565765-13-9.mol | [Molecular Weight]
482.43 |
| Hazard Information | Back Directory | [Uses]
JC-010a is a selective SHP2 allosteric inhibitor. JC-010a inhibits cancer cells proliferation. JC-010a can be used for the research of cancer[1]. | [References]
[1] Lu X, et al. JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers. Cancer Lett. 2024 Feb 1;582:216517. DOI:10.1016/j.canlet.2023.216517 |
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