| Identification | Back Directory | [Name]
CRAMP-18 (mouse) | [CAS]
256639-17-5 | [Synonyms]
CRAMP 18
CRAMP-18 (MOUSE)
CATHELICIDIN-RELATED ANTIMICROBIAL PEPTIDE 18AA (MOUSE)
H-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-OH
H-GLY-GLU-LYS-LEU-LYS-LYS-ILE-GLY-GLN-LYS-ILE-LYS-ASN-PHE-PHE-GLN-LYS-LEU-OH (MOUSE)
CRAMP-18 (mouse) trifluoroacetate salt H-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-OH trifluoroacetate salt
L-Leucine, glycyl-L-α-glutamyl-L-lysyl-L-leucyl-L-lysyl-L-lysyl-L-isoleucylglycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-lysyl-
Glycyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-lysyl-L-lysyl-L-isoleucylglycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-lysyl-L-leucine | [Molecular Formula]
C101H171N27O24 | [MDL Number]
MFCD08702727 | [MOL File]
256639-17-5.mol | [Molecular Weight]
2147.6 |
| Chemical Properties | Back Directory | [Boiling point ]
2199.6±65.0 °C(predicted) | [density ]
1.230±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
3.37±0.10(predicted) | [Sequence]
H-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-OH |
| Hazard Information | Back Directory | [Uses]
CRAMP-18 (mouse) is an antibiotic peptide without hemolytic activity. CRAMP-18 (mouse) has good inhibitory activity against Gram-negative bacteria, such as S. typhimurium and P. aeruginosa. CRAMP-18 (mouse) has the potential to study antifungal, antibacterial and antitumor[1][2]. | [References]
[1] Shin SY, et al. CRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity. Biochem Biophys Res Commun. 2000 Sep 7;275(3):904-9. DOI:10.1006/bbrc.2000.3269
[2] Kang SW, et al. CRAMP analog having potent antibiotic activity without hemolytic activity. Protein Pept Lett. 2002 Aug;9(4):275-82. DOI:10.2174/0929866023408643 |
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