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2568842-26-0

2568842-26-0 Structure

2568842-26-0 Structure
IdentificationBack Directory
[Name]

JAK2-IN-9
[CAS]

2568842-26-0
[Synonyms]

JAK2-IN-9
Hazard InformationBack Directory
[Uses]

JAK2-IN-9 (Compound A8) is a selective JAK2 inhibitor (IC50: 5 nM). JAK2-IN-9 inhibits the phosphorylation of JAK2, STAT3, and STAT5. JAK2-IN-9 has metabolic stabilities. JAK2-IN-9 induces apoptosis. JAK2-IN-9 can be used for research of myeloproliferative neoplasms (MPNs)[1].
[IC 50]

JAK2
[References]

[1] Tian Y, et al Discovery of N-(4-(Aminomethyl)phenyl)-5-methylpyrimidin-2-amine Derivatives as Potent and Selective JAK2 Inhibitors. ACS Med Chem Lett. 2023 Aug 1;14(8):1113-1121. DOI:10.1021/acsmedchemlett.3c00251
2568842-26-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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