| Identification | Back Directory | [Name]
Benz[cd]indole-4-propanoic acid, 1,2-dihydro-6-[[(2-methoxyphenyl)sulfonyl]amino]-1-methyl-2-oxo- | [CAS]
2570470-39-0 | [Synonyms]
3-[6-(2-Methoxyphenylsulfonamido)-1-methyl-2-oxo-1,2-dihydrobenzo[cd]indol-4-yl]propanoic Acid
Benz[cd]indole-4-propanoic acid, 1,2-dihydro-6-[[(2-methoxyphenyl)sulfonyl]amino]-1-methyl-2-oxo- | [Molecular Formula]
C22H20N2O6S | [MOL File]
2570470-39-0.mol | [Molecular Weight]
440.47 |
| Hazard Information | Back Directory | [Uses]
BET-IN-6 is a potent and high affnity BRD2/BRD4 inhibitor. BET-IN-6 is the ligand for target protein BRD2/4, and is used for the systhesis of PROTAC BRD2/BRD4 degrader-1 (HY-130612)[1]. | [References]
[1] Jiang F, et al. Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.Bioorg Med Chem.?2020 Jan 1;28(1):115181. DOI:10.1016/j.bmc.2019.115181 |
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