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2573211-25-1

2573211-25-1 Structure

2573211-25-1 Structure
IdentificationBack Directory
[Name]

BIO-7488
[CAS]

2573211-25-1
[Synonyms]

BIO-7488
Imidazo[1,2-a]pyrimidine-6-carboxamide, 7-(1-methylethoxy)-2-(1-methyl-2-oxabicyclo[2.1.1]hex-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)-
[Molecular Formula]

C23H25N7O3
[MOL File]

2573211-25-1.mol
[Molecular Weight]

447.49
Chemical PropertiesBack Directory
[density ]

1.52±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

7.44±0.46(predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

BIO-7488 is a potent, selective, oral active and CNS-penetrant IRAK4 inhibitor with the IC50 of 0.6 nM and > 30 μM for IRAK4 and hERG, respectively[1].
[IC 50]

hIRAK4: 0.6 nM (IC50)
[References]

[1] Ryan Evans, et al. The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke. J.Med. Chem. 2024.
2573211-25-1 suppliers list
Company Name: Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd  
Tel: 15317229551
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Company Name: Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd.  
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Company Name: Suzhou Haiben Pharmaceutical Co., Ltd  
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Company Name: TargetMol Chemicals Inc.  
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Website: https://www.targetmol.cn/
Company Name: CAREBIO PHARMA  
Tel: 186669426717 18501057619;
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Company Name: Zhengzhou Haode Pharmaceutical Technology Co.,Ltd  
Tel: 18037386321
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