| Identification | Back Directory | [Name]
4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2,3-triazol-1-yl)ethoxy]-, hydrochloride (1:1) | [CAS]
257938-36-6 | [Synonyms]
ZD4190 HCl
ZD-4190 HCl
ZD-4190 hydrochloride
4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2,3-triazol-1-yl)ethoxy]-, hydrochloride (1:1) | [Molecular Formula]
C19H17BrClFN6O2 | [MOL File]
257938-36-6.mol | [Molecular Weight]
495.74 |
| Hazard Information | Back Directory | [Description]
ZD-4190 is a potent VEGFR inhibitor. ZD4190 prevents tumour outgrowth in a model of minimal residual carcinoma in deep tissues. | [Uses]
ZD-4190 hydrochloride is a potent VEGFR inhibitor with anti-tumor activity. ZD-4190 hydrochloride can delay the growth of MDA-MB-435 tumors by inhibiting tumor cell proliferation and angiogenesis[1]. | [References]
[1] PET imaging of early response to the tyrosine kinase inhibitor ZD4190 DOI:10.1007/s00259-011-1742-z |
|
|