| Identification | Back Directory | [Name]
Pyrazino[1,2-a]benzimidazole, 2-[2-(4-bromophenyl)ethyl]-1,2,3,4-tetrahydro- | [CAS]
2582758-47-0 | [Synonyms]
mGluR2 modulator 4
Pyrazino[1,2-a]benzimidazole, 2-[2-(4-bromophenyl)ethyl]-1,2,3,4-tetrahydro- | [Molecular Formula]
C18H18BrN3 | [MOL File]
2582758-47-0.mol | [Molecular Weight]
356.26 |
| Hazard Information | Back Directory | [Uses]
mGluR2 modulator 4 (compound 47) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.8 μM. mGluR2 modulator 4 can be used for researching antipsychotic[1]. | [IC 50]
mGluR2: 0.8 μM (EC50) | [References]
[1] Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs). Eur J Med Chem. 2020;186:111881. DOI:10.1016/j.ejmech.2019.111881 |
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