2585643-97-4

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2585643-97-4 Structure

Chemical Properties	Back Directory
[Boiling point ] 589.8±50.0 °C(predicted)
[density ] 1.25±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 7.23±0.10(predicted)

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[Uses] DA-023 (Compound 4) is a selective positive allosteric modulator (PAM) of EAAT2 with an EC50 value of 1 nM[1].
[References] [1] Fontana ACK, et al. Synthesis and Structure-Activity Relationships for Glutamate Transporter Allosteric Modulators. J Med Chem. 2024;67(8):6119-6143. DOI:10.1021/acs.jmedchem.3c01909

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