| Identification | Back Directory | [Name]
ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride | [CAS]
25913-34-2 | [Synonyms]
Dimaten
Nonflamin
Tinoridine HCl
Einecs 247-342-9
Y-3642 hydrochloride
Tinoridine Hydrochloride
Tenolinidine hydrochloride
Tenocyclidine hydrochloride
Tinoridine Hydrochloride USP/EP/BP
Tenoridine Hydrochloride Impurities
Tinoridine hydrochloride Y-3642 hydrochloride
2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-
2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine hydrochloride
2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-C)pyridine monohydrochloride
ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride
2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic Acid Ethyl Ester Hydrochloride
ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride USP/EP/BP
Thieno(2,3-C)pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-amino-6-benzyl-, ethyl ester, monohydrochloride
Thieno(2,3-C)pyridine-3-carboxylic acid, 2-amino-4,5,6,7-hexahydro-6-(phenylmethyl)-, ethyl ester, monohydrochloride
Thieno[2,3-c]pyridine-3-carboxylic acid, 2-aMino-4,5,6,7-tetrahydro-6-(phenylMethyl)-, ethyl ester, Monohydrochloride | [EINECS(EC#)]
247-342-9 | [Molecular Formula]
C17H21ClN2O2S | [MDL Number]
MFCD01680536 | [MOL File]
25913-34-2.mol | [Molecular Weight]
352.879 |
| Chemical Properties | Back Directory | [Melting point ]
234-235° (dec) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO : ≥ 31 mg/mL (87.85 mM) | [form ]
Solid | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Tinoridine hydrochloride is a nonsteroidal anti-inflammatory agent and also has potent radical scavenger and antiperoxidative activity. | [Definition]
ChEBI: Tinoridine hydrochloride is a thienopyridine. | [in vivo]
CCl4 aministration produces a marked decrease in the concentrations of liver microsomal cytochrome P-450 and G6Pase, indicating that hepatic endoplasmic reticulum function is disrupted. Prior treatment of the animals with tinoridine (100 mg/kg) significantly reduces the CCl4-induced alterations in the enzyme activities, and a rapid recovery toward the normal values is observed[2]. | [References]
[1] O Shimada, et al. Hydroxyl radical scavenging action of tinoridine. Agents Actions. 1986 Nov;19(3-4):208-14.
[2] Yasuda H, et al. The protective effect of tinoridine against carbon tetrachloride hepatotoxicity. Toxicol Appl Pharmacol. 1980 Mar 15;52(3):407-13. DOI:10.1016/0041-008x(80)90335-x |
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