| Chemical Properties | Back Directory | [Boiling point ]
806.141±75.00 °C(Press: 760.00 Torr)(predicted) | [density ]
2.160±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
0.815±0.28(predicted) |
| Hazard Information | Back Directory | [Uses]
HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, with IC50 values ??of 17.2 μM and 67.8 μM for HldA/E, respectively. HldA/E-IN-1 can be used in the study of anti-bacterial infection[1]. | [IC 50]
HldA: 17.2 μM (IC50); HldE: 67.8 μM (IC50) | [References]
[1] Cao J, et al. Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharide. Bioorg Chem. 2024 Aug 30;153:107767. DOI:10.1016/j.bioorg.2024.107767 |
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