| Identification | Back Directory | [Name]
POLYSARCOSINE | [CAS]
25951-24-0 | [Synonyms]
GlycineImpurity6
Glycine EP Impurity F
sarcosine homopolymer
polysarcosine mol wt 1000-5000
Glycine Impurity 6(Glycine EP Impurity F) | [Molecular Formula]
C3H7NO2 | [MOL File]
25951-24-0.mol | [Molecular Weight]
89.09 |
| Hazard Information | Back Directory | [Description]
Polysarcosine50 is an amine-functionalized hydrophilic polymer.1 It has been used in the synthesis of catechol-functionalized copolypeptoids that can be used to solubilize manganese oxide nanoparticles in aqueous solvents. Surface modification of liposomes with polysarcosine polymers between 10 and 400 units long have been used to increase circulation half-life.2WARNING This product is not for human or veterinary use. | [Definition]
ChEBI:Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine. It has a role as a glycine transporter 1 inhibitor, a glycine receptor agonist, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a N-alkylglycine, a N-methyl-amino acid and a member of N-methylglycines. It is a conjugate base of a sarcosinium. It is a conjugate acid of a sarcosinate. It is a tautomer of a sarcosine zwitterion. | [References]
[1] H. GEBRU. Brønsted base mediated one-pot synthesis of catechol-ended amphiphilic polysarcosine-b-poly(N-butyl glycine) diblock copolypeptoids[J]. Pure and Applied Chemistry, 2018, 91 1: 363-374. DOI: 10.1515/pac-2018-0604
[2] BENJAMIN WEBER. Solution Properties of Polysarcosine: From Absolute and Relative Molar Mass Determinations to Complement Activation[J]. Macromolecules, 2018, 51 7: 2653-2661. DOI: 10.1021/acs.macromol.8b00258 |
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