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259667-25-9

259667-25-9 Structure

259667-25-9 Structure
IdentificationBack Directory
[Name]

(3R)-3-(2-chlorophenyl)-1-(2-diethylaminoethyl)-3-hydroxy-2-oxo-4-(trifluoromethyl)indole-6-carboxamide
[CAS]

259667-25-9
[Synonyms]

686
SM130
SM 130
SM-130,686, CID9804743
(3R)-3-(2-chlorophenyl)-1-(2-diethylaminoethyl)-3-hydroxy-2-oxo-4-(trifluoromethyl)indole-6-carboxamide
[Molecular Formula]

C22H23ClF3N3O3
[MOL File]

259667-25-9.mol
[Molecular Weight]

469.885
Chemical PropertiesBack Directory
[Melting point ]

173 °C
Hazard InformationBack Directory
[Uses]

SM-130686 is an oxindole derivative and an active GH secretagogue (GHS). SM-130686 stimulates GH release with a Half-maximum stimulation of 6.3 nM. SM-130686 has an orally active[1].
[References]

[1] J Nagamine, et al. Pharmacological profile of a new orally active growth hormone secretagogue, SM-130686. J Endocrinol. 2001 Dec;171(3):481-9. DOI:10.1677/joe.0.1710481
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