| Identification | Back Directory | [Name]
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN | [CAS]
259869-55-1 | [Synonyms]
JW 133
CS-317
JWH 133
JWH 133, >=98%
JWH 133 (in Tocrisolve 100)
JWH 133 (in Tocrisolve(TM) 100)
JW 133 (10 mg/mL in Methyl Acetate)
3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC
3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol
(6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN
3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC, 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol
(6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene
(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-(6H)-dibenzo[b.d]pyrane
6H-Dibenzo[b,d]pyran, 3-(1,1-diMethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-triMethyl-, (6aR,10aR)- | [Molecular Formula]
C22H32O | [MDL Number]
MFCD06795847 | [MOL File]
259869-55-1.mol | [Molecular Weight]
312.49 |
| Chemical Properties | Back Directory | [Boiling point ]
382.0±42.0 °C(Predicted) | [density ]
0.950±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
Chloroform, Ethyl Acetate | [form ]
Oil | [color ]
Clear Colorless |
| Hazard Information | Back Directory | [Uses]
JW 133 is an intermediate used to synthesize potent CB2-Selective Cannabinoid Receptor Ligands such as 4-oxo-1,4-dihydroquinoline-3-carboxamides and 3-(1'',1''-Dimethylbutyl)-1-deoxy-Δ8-THC analogs. | [Definition]
ChEBI: JWH-133 is a dibenzopyran that is Delta(9)-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. It has a role as a CB2 receptor agonist, an antineoplastic agent, a vasodilator agent, an anti-inflammatory agent, an apoptosis inhibitor, an analgesic and an opioid analgesic. It is a dibenzopyran, an organic heterotricyclic compound and a benzochromene. | [Biological Activity]
Potent CB 2 selective agonist (K i = 3.4 nM). Approx. 200-fold selective over CB 1 receptors. Active in vivo , reducing spasticity in a murine model of multiple sclerosis. Also available in water soluble emulsion ((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran ). | [storage]
Store at -20°C |
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