| Identification | Back Directory | [Name]
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic | [CAS]
2616-64-0 | [Synonyms]
UDP-g acid
UDP-glucuronic acid
UDP-D-glucuronic acid
UDP-alpha-D-glucuronic acid
Uridine diphosphoglucuronic acid
Uridine pyrophosphoglucuronic acid
Uridine diphosphate glucuronic acid
Uridine 5′-diphosphoglucuronic acid (UDP-glucuronic acid)
Uridine 5'-(trihydrogen diphosphate)mono-α-D-glucopyranuronosyl
α-D-Glucopyranuronic acid, 1→P'-ester with uridine 5'-(trihydrogen diphosphate)
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic USP/EP/BP | [Molecular Formula]
C15H22N2O18P2 | [MDL Number]
MFCD15145135 | [MOL File]
2616-64-0.mol | [Molecular Weight]
580.28 |
| Hazard Information | Back Directory | [Description]
An intermediate
in the phase II reaction that results in the formation of glucuro_x0002_nic acid conjugates of xenobiotics which contain substituents
such as hydroxyl, amino, or sulfhydryl groups, forming the O-,
N-, and S-glucuronides, respectively. UDPGA is formed by
two reactions: (i) the formation of UDPG from UTP and glucose 1-phosphate and (ii) the formation of UDPGA from
UDPG. The two reactions are catalyzed by UDPG pyrophosphorylase and UDPG dehydrogenase, respectively, whereas
glucuronide formation is catalyzed by glucuronosyltransferase.
Glucuronide formation from xenobiotics is common in all animal groups except insects. | [Definition]
ChEBI: A UDP-sugar having alpha-D-glucuronic acid as the sugar component. |
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