| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2619854-01-0 | [Synonyms]
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]
cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal) | [Molecular Formula]
C63H81N19O7 | [MOL File]
2619854-01-0.mol | [Molecular Weight]
1216.47 |
| Hazard Information | Back Directory | [Uses]
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively[1]. | [References]
[1] Sandeep Lohan, et al. Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties. J Med Chem. 2022 Jan 13;65(1):665-687. DOI:10.1021/acs.jmedchem.1c01782 |
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