| Identification | Back Directory | [Name]
L-Phenylalanine, N-benzoyl-, (2R)-2-[[(4-bromophenyl)sulfonyl]amino]-3-phenylpropyl ester | [CAS]
2630388-03-1 | [Synonyms]
ASPER-29
L-Phenylalanine, N-benzoyl-, (2R)-2-[[(4-bromophenyl)sulfonyl]amino]-3-phenylpropyl ester | [Molecular Formula]
C31H29BrN2O5S | [MOL File]
2630388-03-1.mol | [Molecular Weight]
621.54 |
| Hazard Information | Back Directory | [Uses]
ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer[1]. | [IC 50]
cathepsin L: 6.03 μM (IC50); cathepsin S: 5.02 μM (IC50) | [References]
[1] Haoqiang Huang, et al. Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells. Bioorg Med Chem Lett. 2022 Nov 23;80:129087. DOI:10.1016/j.bmcl.2022.129087 |
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