| Identification | Back Directory | [Name]
L-PriMapterin | [CAS]
2636-52-4 | [Synonyms]
L-erythro-
L-PriMapterin
7 Biopterin,7Biopterin
2-AMino-7-[(1R,2S)-1,2-dihydroxypropyl]-4(3H)-pteridinone
4(3H)-Pteridinone, 2-amino-7-[(1R,2S)-1,2-dihydroxypropyl]- | [Molecular Formula]
C9H11N5O3 | [MDL Number]
MFCD27978165 | [MOL File]
2636-52-4.mol | [Molecular Weight]
237.215 |
| Chemical Properties | Back Directory | [Melting point ]
>255°C (dec.) | [Boiling point ]
502.6±53.0 °C(Predicted) | [density ]
1.86±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Acid (Slightly) | [form ]
Solid | [pka]
14.62±0.20(Predicted) | [color ]
Light Beige to Brown | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
7-Biopterin is a 7-substituted pterin. It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD) in vitro and levels are elevated in the urine of hyperphenylalaninemia patients carrying heterozygous mutations in the PCBD gene encoding PCD. | [Uses]
7-Substituted pterins, a new class of mammalian pteridines. Primapterin, Anapterin, and 6-Oxo-primapterin, three new 7-substituted pterins identified in a patient with hyperphenylalaninemia. | [References]
[1] B TH?NY. Hyperphenylalaninemia with high levels of 7-biopterin is associated with mutations in the PCBD gene encoding the bifunctional protein pterin-4a-carbinolamine dehydratase and transcriptional coactivator (DCoH).[J]. American journal of human genetics, 1998, 62 6: 1302-1311. DOI: 10.1086/301887
[2] H.-CH. CURTIUS . Primapterin, anapterin, and 6-oxo-primapterin, three new 7-substituted pterins identified in a patient with hyperphenylalaninemia[J]. Biochemical and biophysical research communications, 1988, 153 2: Pages 715-721. DOI: 10.1016/s0006-291x(88)81153-7 |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|