| Identification | Back Directory | [Name]
10H-6,9a-Ethano-1H-pyrido[1',2':3,4]imidazo[1,2-c]pyrimidin-1-one, 3-[[3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]phenyl]methoxy]-6,7,8,9-tetrahydro- | [CAS]
2637485-13-1 | [Synonyms]
Lp-PLA2-IN-6
10H-6,9a-Ethano-1H-pyrido[1',2':3,4]imidazo[1,2-c]pyrimidin-1-one, 3-[[3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]phenyl]methoxy]-6,7,8,9-tetrahydro- | [Molecular Formula]
C25H21F5N4O3 | [MOL File]
2637485-13-1.mol | [Molecular Weight]
520.45 |
| Hazard Information | Back Directory | [Uses]
Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has?the?potential?for?neurodegenerative related diseases research[1]. | [References]
[1] Qiong Xiao, et al. Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof. CN112574221B. |
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