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2638507-71-6

2638507-71-6 Structure

2638507-71-6 Structure
IdentificationBack Directory
[Name]

2H-1,3-Oxazin-2-one, 3-(4-chloro-3-fluorophenyl)-4-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-ethoxycyclohexyl)-1H-benzimidazol-2-yl]tetrahydro-, (4S)-
[CAS]

2638507-71-6
[Synonyms]

EP300/CBP-IN-1
2H-1,3-Oxazin-2-one, 3-(4-chloro-3-fluorophenyl)-4-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-ethoxycyclohexyl)-1H-benzimidazol-2-yl]tetrahydro-, (4S)-
[Molecular Formula]

C30H32ClFN4O4
[MOL File]

2638507-71-6.mol
[Molecular Weight]

567.05
Chemical PropertiesBack Directory
[Boiling point ]

728.1±60.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Predicted)
[pka]

4.67±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

EP300/CBP-IN-1 (compound 172) is a potent EP300/CBP inhibitor with IC50s of 2.3 nM and 2.1 nM for CBP BRD and EP300 BRD, respectively. EP300/CBP-IN-1 has the inhibitory effect on the proliferation of prostate cancer CWR22RV1 cells[1].
[References]

[1] Lei Fan, et al. An EP300/CBP inhibitor. CN112574189A.
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