| Chemical Properties | Back Directory | [Boiling point ]
834.5±65.0 °C(Predicted) | [density ]
1.194±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.97±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1]. | [Biological Activity]
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1]. | [IC 50]
Bcl-xL | [References]
[1]. Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947. |
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