| Hazard Information | Back Directory | [Uses]
M1/M2/M4 muscarinic agonist 1 (Compound 42) is a muscarinic M4/M1/M2 agonist with EC50 values of 6.5, 26 and 210 nM for M4/M1/M2, respectively. M1/M2/M4 muscarinic agonist 1 can be used for research on mental diseases, such as schizophrenia, delusion, etc[1]. | [IC 50]
mAChR1: 26 nM (EC50); mAChR2: 210 nM (EC50); mAChR4: 6.5 nM (EC50) | [References]
[1] Christopher G Thomson, et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists. ACS Med. Chem. Lett. 2023. Nov 6. |
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