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2640647-90-9

2640647-90-9 Structure

2640647-90-9 Structure
IdentificationBack Directory
[Name]

CCT374705
[CAS]

2640647-90-9
[Synonyms]

CCT374705
[Molecular Formula]

C21H18ClF3N4O2
[MOL File]

2640647-90-9.mol
[Molecular Weight]

450.84
Chemical PropertiesBack Directory
[Boiling point ]

555.057±50.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.536±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

0.623±0.60(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro. CCT374705 effectively inhibits tumor growth in a lymphoma xenograft mouse model[1].
[References]

[1] Harnden AC, et al. Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones. J Med Chem. 2023 Apr 27;66(8):5892-5906. DOI:10.1021/acs.jmedchem.3c00155
2640647-90-9 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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