2642181-22-2

Directory

2642181-22-2 Structure

Chemical Properties	Back Directory
[density ] 1.374±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 3.257±0.10(predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min)[1].
[IC 50] MMP2: 0.22 nM (IC₅₀); MMP-12: 250 nM (IC₅₀); MMP13: 240 nM (IC₅₀)
[References] [1] Takeuchi T, et al. Discovery of TP0597850: A Selective, Chemically Stable, and Slow Tight-Binding Matrix Metalloproteinase-2 Inhibitor with a Phenylbenzamide-Pentapeptide Hybrid Scaffold. J Med Chem. 2023 Jan 12;66(1):822-836. DOI:10.1021/acs.jmedchem.2c01698

2642181-22-2 suppliers list

Tags:2642181-22-2 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login