| Identification | Back Directory | [Name]
DIETHYL-12-BROMODODECYLPHOSPHONATE | [CAS]
264231-28-9 | [Synonyms]
LUN 31289
diethyl 12-bromodecylphosphonate
DIETHYL-12-BROMODODECYLPHOSPHONATE
Phosphonic acid, (12-bromododecyl)-, diethyl ester (9CI) | [Molecular Formula]
C16H34BrO3P | [MDL Number]
MFCD11046105 | [MOL File]
264231-28-9.mol | [Molecular Weight]
385.32 |
| Hazard Information | Back Directory | [Description]
diethyl 12-bromodecylphosphonate contains bromine and phosphonate moieties. The bromine is a good leaving group and can undergo nucleophilic substitutions. The phosphonate group acts as chelating agent. | [Uses]
Diethyl 12-bromododecylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Alkyl-Chain | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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