| Hazard Information | Back Directory | [Uses]
ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1]. | [References]
[1] Li, Jinping, et al. Rock inhibitor, preparation method therefor and use thereof. WO2021093795. |
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