| Chemical Properties | Back Directory | [Boiling point ]
714.7±70.0 °C(predicted) | [density ]
1.318±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [solubility ]
Ethanol: Slightly soluble
Methanol: Slightly soluble | [form ]
Solid | [pka]
14.22±0.40(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro[1]. | [References]
[1] Bi Y, et al. A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis. Genes Dis. 2023 Apr 3;11(1):479-494. DOI:10.1016/j.gendis.2023.02.035 |
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