| Identification | Back Directory | [Name]
Quinoline, 4-[[1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-6-methoxy-7-[3-(4-morpholinyl)propoxy]- | [CAS]
2657720-04-0 | [Synonyms]
ALK5-IN-6
Quinoline, 4-[[1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-6-methoxy-7-[3-(4-morpholinyl)propoxy]- | [Molecular Formula]
C28H36N4O5 | [MOL File]
2657720-04-0.mol | [Molecular Weight]
508.61 |
| Hazard Information | Back Directory | [Uses]
ALK5-IN-6 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-6 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 1)[1]. | [References]
[1] Tang Feng, et al. Pyrazoles. Patent WO2021129621A1. |
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