| Identification | Back Directory | [Name]
Propanamide, N-[(1S,2R)-2-(3,5-difluorophenyl)-1-methyl-2-[[1-(1,2,4-triazolo[4,3-a]pyridin-6-yl)-1H-benzotriazol-5-yl]oxy]ethyl]-2,2-difluoro- | [CAS]
2662908-25-8 | [Synonyms]
Glucocorticoid receptor-IN-1
Propanamide, N-[(1S,2R)-2-(3,5-difluorophenyl)-1-methyl-2-[[1-(1,2,4-triazolo[4,3-a]pyridin-6-yl)-1H-benzotriazol-5-yl]oxy]ethyl]-2,2-difluoro- | [Molecular Formula]
C24H19F4N7O2 | [MOL File]
2662908-25-8.mol | [Molecular Weight]
513.45 |
| Hazard Information | Back Directory | [Uses]
Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-1 exhibits very good transcriptional repressive activity with an IC50 of 2.11 nM against hMMP1, and transcriptional activation activity with an EC50 of 5.59 nM against MMTV[1]. | [References]
[1] Guoli Zhang, et al. Benzo[d][1,2,3]triazole ether compound. WO2021136431. |
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