| Identification | Back Directory | [Name]
Benzamide, N-[(1S)-2-cyano-1-[4-(ethylsulfonyl)phenyl]ethyl]-4-[(cyclopropylmethyl)(3,5-dicyclopropylphenyl)amino]- | [CAS]
2664106-24-3 | [Synonyms]
RORγt agonist 3
Benzamide, N-[(1S)-2-cyano-1-[4-(ethylsulfonyl)phenyl]ethyl]-4-[(cyclopropylmethyl)(3,5-dicyclopropylphenyl)amino]- | [Molecular Formula]
C34H37N3O3S | [MOL File]
2664106-24-3.mol | [Molecular Weight]
567.74 |
| Chemical Properties | Back Directory | [Boiling point ]
841.5±65.0 °C(Predicted) | [density ]
1.273±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
12.73±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
RORγt agonist 3 is a potent agonist of RORγt. RORγt agonist 3 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 3 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136326A1, compound 23)[1]. | [References]
[1] Liu Bin, et al. Aromatic amides and their use in pharmaceuticals. Patent WO2021136326A1. |
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| Company Name: |
Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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