| Identification | Back Directory | [Name]
4,4-DIMETHYL-2-OXAZOLIDINONE | [CAS]
26654-39-7 | [Synonyms]
DMO
DMRTA1
4,4-Dimethyloxazolidinone
4,4-dimethyl-oxazolidin-2...
4,4-DIMETHYL-2-OXAZOLIDINONE
2-Oxazolidinone,4,4-dimethyl-
4,4-diMethyl-oxazolidin-2-one
4,4-dimethyl-oxazolidine-2-one
4,4-Dimethyl-1,3-oxazolidin-2-one
4,4-DIMETHYL-2-OXAZOLIDINONE STANDARD
ANTI-DMRTA1 (C-TERM) antibody produced in rabbit
Doublesex- and mab-3-related transcription factor A1 | [Molecular Formula]
C5H9NO2 | [MDL Number]
MFCD04038702 | [MOL File]
26654-39-7.mol | [Molecular Weight]
115.13 |
| Hazard Information | Back Directory | [Synthesis]
4,4-Dimethyloxazolidin-2-one (DMO) was synthesized as follows: 2-amino-2-methyl-1-propanol (10.0 g, 112 mmol) was mixed with urea (13.5 g, 224 mmol), and the mixture was heated and reacted for 1 hour at 170-180 °C, followed by heating up to 210-220 °C and continued heating for 1 hour. After completion of the reaction, it was cooled to room temperature and the reaction mixture was dissolved in water (50 mL). Dichloromethane (DCM, 5 x 50 mL) extraction was performed with the aqueous solution. The organic phases were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to afford 4,4-dimethyloxazolidin-2-one 10.3 g in 80% yield. The product was identified by 1H NMR (CDCl3): δ 6.13 (br s, 1H, NH), 4.07 (s, 2H, CH2), 1.32 (s, 6H, 2 CH3) ppm; 13C NMR (CDCl3) δ 159.4,77.1,55.4,27.7 ppm. | [References]
[1] Asian Journal of Chemistry, 2011, vol. 23, # 2, p. 929 - 930
[2] Patent: WO2015/68159, 2015, A2. Location in patent: Paragraph 00121-00122 |
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| Company Name: |
Energy Chemical
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021-021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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