2675-35-6

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2675-35-6 Structure

Identification	Back Directory
[Name] Sivifene
[CAS] 2675-35-6
[Synonyms] A007 A-007 A 007 sivifene Unii-xav05295I5 Sivifene, 10 mM in DMSO YOQPCWIXYUNEET-UHFFFAOYSA-N 4,4'-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone Bis(4-hydroxyphenyl)methanone (2,4-dinitrophenyl)hydrazone Methanone, bis(4-hydroxyphenyl)-, 2-(2,4-dinitrophenyl)hydrazone
[Molecular Formula] C19H14N4O6
[MDL Number] MFCD00339445
[MOL File] 2675-35-6.mol
[Molecular Weight] 394.34

Hazard Information	Back Directory
[Hazard] Moderately toxic by ingestion.
[Uses] Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors[1].
[References] [1] Eilender D, et al. 4,4'-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007): a topical treatment for cutaneous metastases from malignant cancers. Cancer Chemother Pharmacol. 2006 Jun;57(6):719-26. DOI:10.1007/s00280-005-0124-2

Safety Data	Back Directory
[Toxicity] LD50 oral in rat: 4300mg/kg

Spectrum Detail	Back Directory
[Spectrum Detail] Sivifene(2675-35-6)¹HNMR

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